If you're gonna work up to running in the five fingers, take it slow. When I started, I laughed at the recommendation to run less than a mile at a time when running in five fingers for the first time, and ran my usual 3 mile morning courses... Can tell you I spent more days recovering then running each week (something like 3-4 days off per day of running). My tendons and ankle muscles weren't used to all that work yet.
Eventually, I was able to run without needing a recovery day, but I feel like that time period of getting used to running in them would have been shorter or more effective if I had actually listened to the advice of taking it slow, even if it doesn't feel like you're getting a workout.
I wear the SeeYa running ones, great breathability so feet don't get all sweaty and light as air. Spyridons are great for hiking, good traction, a bit more sole so that the sharp rocks don't hurt. Doesn't dry out as quickly after crossing streams compared to the KSO or trek multisport.