Marsha, in the old days we would always wear two pairs of socks: thin liners and thick wool socks. Then our boots were sized to fit that, and we didn't get blisters.
Now so many backpackers are using super lightweight low cut shoes. That's OK, but you have to have the right socks to make it all fit correctly. Then, after the boots are broken in, you still have to do some training until you can go and keep going without blisters. Hot spots are just the precursors to blisters.
Back when I was a kid on the school track team, the coach made us paint our feet with tincture of benzoin before we put our track shoes on. Two things. First, it is a little sticky, so the socks are less likely to rub. Secondly, the stuff has some rubbing alcohol in it, and over a period of time that tends to toughen the skin. It will leave a dark brown stain on light colored socks.
If that doesn't work for you, then you can simply tape the soft parts of your feet with athletic tape.