My knee pain was cut by 80-90% when I started backpacking in "barefoot" shoes. And, after a decade of not being able to jog across a cross walk in "runners" without pissing it off for days, I discovered I can literally run again in these shoes, or barefoot, with no problems. (I seldom run anymore but it's nice to know I can when I want)
So, I got rid of all my day to day shoes that were cushioned in the heal, were snug fitting, had arch support, and all the other stuff we've been told for yrs we "need" to take care of our feet. I have since tried on conventional "running shoes" to see what they felt like and I feel severely handicapped.
I'm no PT or podiatrist...and I'm even further from being trendy, but I think there is a lot to be said for wearing a shoe that allows everything to work naturally...at least for some people (maybe most, I don't know).
Don't know if it applies to the OP but this is my experience and observations. I should also note that my total backpack weight is between 7.25 and 10 lbs which I'm sure helps too.
Best of luck to the OP!