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I know people with skin that tough, from intense and prolonged exposure to wind, sun, salt water, and extremes of heat and cold. Basically, they tan their own hides and turn them into leather (my father doesn't need oven mitts, it's kind of horrifying). Then they have trouble with drying and cracking, just like with leather. Scratch-resistant, yes, but they still get infections. And because it's true about slower healing, they are probably MORE likely to get infected once injured, and certainly more prone to scarring.
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