Aqua Mira, Klearwater and Micropur are all the same chlorine dioxide. Aqua Mira requires a 5 minute pre-mixing time. After that, all three have the same "treatment time" -- 15 minutes or so to kill the really small stuff like bacteria and viruses -- longer time in colder water.
However, when it comes to the bigger stuff like cysts -- esp. organisms with a protective shell like cryptosporidia -- treatment time shoots up to 4 hours! Again, this is the same for all three.
To me, a four-hour treatment time is of dubious value -- but I suppose it's theoretically better than using chlorine or iodine, which are both ineffective against crypto, regardless of the length of treatment time.
For those who want to kill all three groups of badies (viruses, bacteria and cysts), the following options can be used:
1. Chemicals only -- Aqua Mira, Klearwater or Micropur -- wait up to 4 hours!
2. Mechanical and chemical - Filter the bigger stuff out first, then treat with chemicals to kill viruses -- only 15 minutes treatment time required, longer if water is really cold -- beats waiting for 4 hours.
3. Chemical and Mechanical - Treat with chemicals to kill viruses first, then filter out the bigger stuff AND any chemical taste. This is my method, and I use Micropur and then a Seychelle inline filter.
4. UV (Steri-Pen, etc.) - Zap the water with UV rays for one minute and kill all three types of baddies. Unfortunately (for me), I use narrow-mouth platy's and the UV tube isn't as effective since it can't reach down far enough into the bottle. Talking with Steri-Pen folks on the phone, they suggest that I treat the water in a cup or equivalent wide-mouth container, then pour the treated water into my Platypus. I find that too much of a hassle, but YMMV.