The bladder should not matter....it is a question of if the hose/line is going to be big or small enough to allow the Sawyer inline to be spliced into that line.
Should be....plus, I would imagine that the adapters for the line will accomodate various tube sizes. (If it is cone shaped, then it should).
Also, are you a trail runner?
If so, then you might want to see about where along the line you will placing the filter so that it is not bouncing around and annoying the hell out of you.
Just make sure that the conections are solid, so it does not leak inside your pack.
Hope that helps.