Perhaps you have made your pack decision already, but I'll add my two cents: I started out using a GoLite Quest plus waterproof liner in 2009 on week-long packrafting trips with 35-40 pound total weight including boat. I was pleased with the Quest: a rolled up Yukon Yak fit snugly in a side sleeve, and the total volume was just adequate for a bunch of food, tarp, 30 degree down bag, down camp/sleepwear, etc. I would not have at all minded the slightly larger Odyssey for a bit more comfort on the weight/volume side, so it's probably a safe bet for you, and a good all'rounder of a large pack if it fits you well.
Due to pack fit (6'0" with a long torso)and my propensity to take my boat with me, I changed to the ULA Epic last Summer. It is perfect for packrafting applications, and the included drybag was appropriately durable (not impervious to fish hooks though and a pack-specific drybag would be even better), but I had to shell out a bit more than I did for the Quest on sale...
I recommend both packs depending on how specialized you want to get, and more importantly, fit.