Well, 120 ibu in a can will probably affect the flavor, what with the lining all dissolved and everything! Ha ha.
Personally, I haven't given much time to the can trend for craft beers because, although its great for light management, the aluminum can is otherwise a trainwreck for holding fine beer. The can does impart flavor, the sharp-edged mouth frustrates a good pour and beer that good deserves a pour rather than a can opener and a shotgun, ho ho. I'll stick with dark brown and deep green bottled beers for the good stuff and cheapass bears in the can for those times when it's appropriate.
Besides, when you're backpacking, nothing explodes on the rocks like a well-lobbed glass bottle.