These debates intrigue me and since I'm at work with some simple FEA tools at hand I modeled up the stake as best I could by scaling the picture and ran the numbers, no hole, centered hole, and offset hole. Obviously, no hole is the strongest, offset hole comes in 2nd, and the centered hole is the weakest, but that is only taking buckling strength into account, and nothing else. With the hole offset like that, and the guyline through it in the way the OP wants it run, the offset hole would apply a twisting moment onto the stake, and that could loosen its grip in the soil, I would assume. If anyone is a civil engineer with experience in anchoring things in dirt, feel free to comment.
Since pictures are worth a thousand words -
And for the record, I put a 100lb compressive load on the stake for my simulations, and that only loaded the weakest stake to 1/4th is rated tensile strength. Also, I had to make it .022" thick to make it weigh ~7.6 grams @ aprox. 0.150 lbs/in^2, 6Al-4V titanium.