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http://www.cancer.gov/clinicaltrials/results/summary/2010/sunscreen-melanoma2010
"In an accompanying editorial, Phyllis Gimotty, Ph.D., and Karen Glanz, Ph.D., of the Center for Clinical Epidemiology and Biostatistics at the University of Pennsylvania School of Medicine wrote: “To our knowledge, the trial’s findings are the first to provide strong evidence for a reduction in the incidence of invasive melanoma after regular application of broad-spectrum sunscreen in adults…. It is unlikely that another trial of comparable scope and rigor will be conducted in the foreseeable future.”
Furthermore, they wrote, although “the question of its efficacy with respect to melanoma prevention should no longer deter scientists or clinicians from recommending sunscreen use,” effective skin cancer prevention should also include avoiding exposure to ultraviolet rays, using clothing to shield skin from the sun, and performing regular skin self examinations.
“This study provides important evidence regarding the role of sunscreen use as part of a range of sun-protective behaviors that effectively reduce risk of melanoma,” commented Margaret Tucker, M.D., of NCI’s Division of Cancer Epidemiology and Genetics."
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