I recently started training with a pair of Merrell TrueGloves. I was hoping to begin to transition to using these for backpacking, as well. I've gotten a couple of blisters caused by using socks that were sliding at the ball, but I have switched to sockless with good result. I'm a fairly novice walker, so your results may vary.
The only thing I'm concerned about is moisture. If you go through even wet ground, the water makes its way through the mesh on the side. I soaked the shoes one afternoon to see how they would dry out and the next morning they were very wet and cold despite being stored indoors. The usual method of sticking them in front of the refrigerator dried them out in good time, but, alas, there is no electricity in the back country so I won't be able to use the refrigerator drying method on the trail ;)
The soles of these are made by Vibram and are similar to the VFF's methinks:
You might notice that I've changed out the laces for spectra. This was a huge improvement as the new laces are about 5' in length and I found it beneficial to have a cord that would slide and somewhat auto-adjust the tension between the eyelets. The original laces had to be individually adjusted at each eyelet which made getting the shoes comfortable a lengthy process every time.
What do you folks who use water-permeable shoes do when it's wet or when you do creek crossings? There are a lot of water crossings in my backyard training trail and I wonder about how this works in an extended trip with one pair of shoes. By further way of anecdote, I will mention that the tops of your feet stay pretty dry, but the bottom of your feet, even just wearing them around stay tacky if you're sockless.
Please help a noob with any feedback. Thanks and sorry for the sub-par camera-phone pics.