I remember a hike from my days of heavy packs and clunky boots when I had horrible, painful blisters. For some reason, it was psychologically much harder to lead the way- I asked my girlfriend to hike in front for the rest of the trip, and it seemed to help. Something about looking down an empty trail that made the pain worse?
Hiking lightweight makes everything easier, of course, whether or not you are alone. I guess that's the bottom line! I do think that when you are hiking alone, you face challenges and uncertain situations differently.