well, your socks will be compressed if their synthetic puffy insulation as you lace up the boot. Also if you size bigger for that, your foot will likely slide around making for a poor climbing fit and giving rise to blisters ect even if your just walking.
If your climbing technical ice, the trango S are too soft for prolonged frontpointing.
The good alpinists do go VERY fast and VERY light, but they know where to cut weight. A boot like the Trango Extreme(?) is designed to insulate as well as to climb well. A much better winter, to even all season, choice then the Trango S. House used La Sportiva Spantik's on his ascent, and that or the Nupse might be a better choice for prolonged winter trips as you can dry out the booties in you bag overnight. Also you could use the Trango Extreme with a VBL sock, not as warm as a full double boot but pretty warm. I've heard of some hardcore climbers using boots like the Spantik with a Intuition liner for winter assents of the 8000m peaks.
The issue with reluctance to try new technologies is that many of them fail to live up to expectations.
For mission critical gear, like my boots, I'd like to stick to technologies that both work and have few opportunities for failure in the field. Inflated socks, would fall outside of that categorizes, IMO.
Also, if you inflate them hard enough to resist the pressure of the laces, I think your going to fins that they bind uncomfortably or burst as you take a step.
IMO, go get the 'standard recommended gear', go get some experience, let us know how it went, AND THEN think about new and radical ways of cutting weight. As fun as it is, I would love to hear your ideas, but once their tempered by experience.