Sounds like you've done a bunch of stuff farther north(with the exception of Mitre Basin), so I'll throw a South Sierra ramble into the mix. Starting at Horseshoe Meadow: Go over either Cottonwood or New Army Pass; Head up toward Mitre Basin, but then go west past Sky Blue Lake over Crabtree Pass and drop into Crabtree Lakes Basin; Continue past Crabtree Lakes and follow Whitney Creek all the way down to the Kern River and head north to Junction Meadow(Whitney Creek is a beautiful, seldom done route that bypasses the JMT north to Wallace Creek and then down to Junction Meadow via Wallace Creek Trail); From Junction Meadow, head west up the Colby Pass trail; ~1/4 mile past Rockslide Lake turn south, cross the Kern Kaweah River, and ascend Pickett Creek(bushwhack initially and then a beautiful streamside scramble). Be sure and follow the east fork of the stream. It will take you into Kaweah Basin, easily one of the most beautiful places in the Sierra IMO. Cross into the west side of the basin and exit via the southernmost saddle on the western rim of the basin into the upper Kern Kaweah River drainage, or drop down the chain of lakes to the north and scramble steeply back down to the Kern Kaweah River and the Colby Pass Trail. Follow the Colby Pass Trail up to ~1 mile below Colby Pass and turn north into Milestone Bowl, a beautiful, wild lonely place. Cross Milestone Pass and drop down into Milestone Basin. From there head east to pick up the trail that goes south into the Kern Canyon or north to Lake South America. Go north to Lake South America. From there you have a couple of options: 1) go north over Harrison Pass and then over Deerhorn pass down past Vidette Lake to pick up the JMT and out either over Kearsarge Pass or Shepherd Pass(hitch back to Horseshoe Mdws or arrange a shuttle pickup); 2) Go by trail from Lake South America directly out over Shepherd Pass. If you have the time and energy, returning via Shepherd Pass would offer short side excursions to Wright Lakes Basin and Wallace Lake Basin, and Williamson Bowl(all worth a visit if you haven't seen them). And Shepherd Pass is a real kick in the butt, not to mention gorgeous, especially if you're coming down well acclimatized. It's my favorite entry into the South Sierra. I have done all of this except Deerhorn Pass-Vidette Lake in slightly shorter sections and can vouch that the route will go. Based on what you have said about your previous experience, you should be able to finish this in around 10 days, but if you decide to do it, I'd suggest you plan for a couple of extra days to just hang out along the way, because you'll be passing through some spectacular country. Whatever you decide to do, best of luck! Lots of class 2 and 3 peaks along the way. Check Secor's book for details.